Reshaping the Future of Cardiac Bypass Surgery


Our artificial graft eliminates the harvesting of vessels for cardiac bypass surgery, which improves the quality of life for patients and reduces costs for the healthcare system.


There are over 800,000 heart bypass surgeries performed every year.  For each bypass surgery, the surgical team create an additional incision(s) to remove, or to harvest, vessels from the patient's legs or arms.  These vessels are then used for the bypasses.


Eliminating this extra surgical step significantly decreases both procedure time for the surgical team and recovery time for the patient.  It decreases the risk of infection[1] and prevents additional scarring, pain, and other complications to the patient.


Current Vein Harvesting Methods

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Global Need 

Cardiovascular Disease (CVD) is the #1 cause of death globally.  Almost two billion adults are at risk for heart disease, a result of worldwide obesity tripling since 1975.[2]


Minimally invasive treatments for cardiac blockages, such as stents, can be helpful in some cases.  But, when more than two arteries are involved, bypass has been the preferred option.[3]  In addition, bypass surgery is typically the method that provides more complete revascularization.[4]



Our founder and CEO, Manny Villafaña, Ph.D.Sc., started Medical 21 to significantly improve the quality

of life for cardiac bypass patients.  

Medical 21 is a developmental stage medical device company.  We are developing and intend to commercialize and market an artificial graft to bypass lesions in the heart and other parts of the body.  Of the 800,000 cardiac bypass surgeries performed every year [5], each uses an average of 2.5 grafts per procedure.[6]


Our revolutionary product has potential to impact these many lives. Manny has put together a team who collectively possess decades of experience in the successful development, manufacturing, sales, and marketing of medical products to the domestic and international healthcare markets.



The Medical 21, Inc. team has a long, proven history of creating incredible and lasting value in the medical device industry.